Epidermodysplasia verruciformis

Epidermodysplasia verruciformis is a rare, lifelong disorder of autosomal recessive inheritance. It is characterized by chronic infection with human papillomavirus that manifests as widespread skin eruptions of flat-to-papillomatous, wartlike lesions and reddish brown pigmented plaques on the trunk, the hands, the upper and lower extremities, and the face. The lesions have a potential to transform into malignant carcinomas during the fourth and fifth decades of life. What would be the appropriate treament for the widespread lesions as seen in this case. View images